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Stands for Monthly Vaginal Bleeding. A synonym for a woman's period, or menstruation.
Megan's MVB was finally over after 5 days.
MVB by Borimir August 16, 2009
Related Words
Most Valuable Bitch, the most important female; the 1st lady. Queen B (Lil' Kim) For Bad Boy Records.
Dat chick is the MVB of th clique ya na, so you best show some respect.
mvb by Pecknarm's MVB December 31, 2006
Doing a girl in the mouth, vaginal, and then butt

or

Massive Vaginal Boner aka crazy swollen clit
Yo brah, I fuckin' MVB'd some freshman last night at that party!
Dude, fucked this chick last night with a fucking MVB. It was bigger than Kenny's cock.
MVB by lielia November 21, 2011
Friend 1: "Does MVB really stand for modesto virtual bathroom?"

Friend 2:"Maybe. Maybe not."
MVB by Horchataisntthatcool17 January 13, 2009
Most Vauluable Button
my previous channel button is my MVB
MVB by Stephanie Light April 2, 2008
Pretty and cool asl

Laid back
Them MVB’s ah different vibe😩💞
MVB by Lover_bou April 24, 2020