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substance 

He's addicted to a substance, which explains his random acts of insanity.
substance by Anonymous July 14, 2003

substance 

An Album By New Order. A Band that spawned from Joy Division. which included songs that people know like blue monday and age of consent.
hey man have you ever listened to new order. yeah i listened to substance just last night after hearing age of consent from that one soffia coppola movie preview.
substance by Ranae December 12, 2007

substance 

Cocaine, heroin, ecstasy, weed, hash, opium, angel dust, ketamine, lsd, uppers, downers, and everything else you can ingest.
That guy's writing had substance, he didn't go 5 pages without mentioning snorting, shooting, smoking, drinking, dissolving or plugging rectally something that was he was going to get high off of. Is that the kind of writing anybody would really want to read over and over for more than a laugh though?
substance by The Original Agahnim January 4, 2022

Substance 

The guy's/girl's bullshit could have been about a sentence long, straight to the point, but instead he/she spent 5 pages of adding in substance to make it sound more interesting/exciting than it actually was.
Substance by The Original Agahnim January 4, 2022

Substance D 

1. Substance D is a fictional addictive amphetamine-like psychoactive drug, also known as "Slow Death", "Death" and "D", that is depicted in Philip K. Dick's novel "A Scanner Darkly". It's derived from the fictional flower "Mors ontologica".

2. By extension, Substance D can refer to amphetamine (speed).
"What he sold me as 'candy' actually turned out to be 'Substance D'."

This is a more subtle way to refer to amphetamine in a conversation if you don't want to attract too much attention.
Substance D by Electric Sheep March 15, 2009

Substance Toddler 

(n.) A person who can only tolerate a small amount of drugs, alcohol, etc.
(n.) A lightweight
Jimmy: Where's Carl?
Ron: He passed out after like 3 beers, man.
Jimmy: What a substance toddler!
Substance Toddler by Ankylosaurus February 21, 2010