FUPA Share definition Flag Accroym that stands for Fat Upper Pussy Area. Commonly seen when women wear tight pants and they have a bulge of fat above their pelvic region. My teacher's pants are so tight, it outlines her FUPA. FUPA by Misty May April 22, 2007 0 0 Get merch Get the FUPA mug. Buy Now — $32.95 See more merch