Rachel: Have you seen this meme? If you squint it looks like John.
Amy: I don't have to squint before you said that I thought it was John.
Rachel: Do you think it could be him? He's been memified!
A person or an entity who will be a meme on the internet forever. Most of the famous people or rather obvious ones are already became memefied (Obama, Trump, Putin). That doesn't mean you cannot be memefied too. You can be memefied overnight if you play your cards right.
Success kid, Scumbag Steve, Disaster Girl, Overly attached girlfriend are only a few of those who became famous after being memefied