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no mames 

It's a mexican slang that has 3 meanings:

1. it's a vulgar or informal way to say "you're kidding"

2. it's a vulgar way to say "stop messing around"

3. sometimes can be used like saying "no way"

4. or when you're scared or desperate and you suddenly say "no mames" just because nervous or something like that and when you say that word is like saying "damn".
guy1: Karina said that you're going around with Jose

girl1: no mames !!!
no mames by Brendiux Le Doux December 5, 2004

no mames 

comes from the word mamar, meaning "suck" in spanish.
Mexican slang for : "you're kidding"
Mexican slang for : "Stop messing around"
guy 1: Yesterday I saw Madonna in my back yard
guy 2: No mames!

guy 1: Maybe you can dress in drag...
guy 2: No mames...
no mames by stardelice August 8, 2004

No mames 

Is a way to say 'don't joke about that' but in a way less serious, like 'no wayy men'
Is only said by close friends.
Is aslo said because a tragic happend unexpectedly.
Carmen descubrió que su novio le fue infiel
- qué?! No mames
No mames by Thaid March 8, 2018

no mames 

mexican slang for fuck off. polo polo says it a lot if you want the correct pronunciation.
girl: i love you
dude: ya no mames cabrona
no mames by chingona April 1, 2005

no mames 

Bree said "where's david" and Gus said "No Mames cabrona"!
no mames by martinezv December 28, 2004

No mames 

A Spanish term that literally translates to “don’t suck”.
NO MAMES SHABNAM!!!!
No mames by shabnamfan2007 June 6, 2025