you're the piss in my pants Share definition Flag used to insult a close friend in a joking hilarious way WARNING: only use around close friends Jose: Jenn, you annoy me so much Jonn: *Gasp* Jose: In fact, you're the piss in my pants you're the piss in my pants by lmaocity July 20, 2016 0 0 Get merch Get the you're the piss in my pants mug. Buy Now — $32.95 See more merch