Tweaknut 

A person who is a freaking spaz.

calm your ass down,damn what a tweaknut!

Tweaknut by jude-e December 5, 2001

tweaknation 

When something or someplace is so tweaked up, so messed up, that it causes the person experiencing it to tweak out or get wildly pissed off.

person 1: "man, my professor told me to stop typing on my laptop during class. like it's literally school."
person 2: "school? more like tweaknation."

tweaknation by amazing-meatball August 6, 2025

Social Tweakout 

a situation where you find yourself in an environment with a large number of people engaging in bizarre or unconventional behavior.

Last night was a social tweakout; it was like a zombie apocalypse, but instead of brains, everyone was after clown noses and meth.

Social Tweakout by FGR301 June 10, 2024