toot the loot Share definition Flag 1. To ingest psychoactive drugs via intranasal inhalation.2. To snort drugs. Beth - Bob just came home and he has some coke. Mary - Hell ya! Let's toot the loot! toot the loot by Gladgal April 21, 2016 0 0 Get merch Get the toot the loot mug. Buy Now — $32.95 See more merch