The act of blowing your runny nose into the cleavage of your female partner, then using the nasal discharge as lubrication to titty fuck her.
Babe my allergies are killing me tonight, can I give you "Tissue Box" and kill two birds with one stone?
by JDizzleFerrizzle March 31, 2009
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to ejaculate so much that you need a whole box of tissues to clean up
Guy 1: ACHOOOO!!!!! u got any tissues?
Guy 2: naw man, earlier i had a tissue box orgasm
by neverbeencaught1007 April 26, 2010
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An Emotional Tissue Box is someone you can come to, to talk about your feelings and emotions. They are there for you, and they are like a tissue box because they quell your tears.

To show how someone is such a good tissue box, call them by a really nice tissue box brand name, like Puffs Plus.
Jonny Waffle: Avery, you dah best.

Avery: I'm here for you man.

Jonny Waffle: You're like Puffs Plus, you Emotional Tissue Box.

Avery: <3
by Jonny Waffle July 14, 2011
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when you think you're going to get caught masturbating so you ejaculate as soon as possible and grab the tissues rapidly causing many tissues to come out as well
Guy 1: Dude my mom almost caught me rubbin it out!
Guy 2: That happened to me too, I had a tissue box orgasm, but my mom didnt even come in my room... FUCK
by neverbeencaught1007 April 26, 2010
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The act of using a bratwurst/sausage to rip the hymen of a female, just like opening the film on a new tissue box
Person 1: Hey man did you snag Jessica's virginity last night?

Person 2: Nah bro I hit her with the German Tissue Box so I wouldn't get blood on my rod.

Person 1: right on!
by Kevin Sanchez February 6, 2018
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An emotionally dead person who has as many emotions as a tissue box
Man: Kayley i love you
Kayley: I dont
Man: you are a tissue box
by Bigballzbabe August 14, 2021
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Meaning 1: you recently had a girlfriend over to watch "Fault in Our Stars".
Meaning 2: you haven't jacked off in over two weeks and finally did.
1) I had Patricia over to my house yesterday and it resulted in an empty tissue box.
2)I had Patricia over to my house yesterday and it resulted in an empty tissue box.
by The Maniacal Sponge May 5, 2016
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