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to ejaculate so much that you need a whole box of tissues to clean up
Guy 1: ACHOOOO!!!!! u got any tissues?
Guy 2: naw man, earlier i had a tissue box orgasm
by neverbeencaught1007 April 25, 2010
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2
when you think you're going to get caught masturbating so you ejaculate as soon as possible and grab the tissues rapidly causing many tissues to come out as well
Guy 1: Dude my mom almost caught me rubbin it out!
Guy 2: That happened to me too, I had a tissue box orgasm, but my mom didnt even come in my room... FUCK
by neverbeencaught1007 April 25, 2010
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