Stands for one of the following forms of motherfucker: motherfucker, motherfucking, motherfuck. The form that is used depends on the context of the situation.
Aye Henry, let's go give that ese the MF work.
by TurnM3Up December 10, 2019
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mf has 2 meanings, often used as:

(i) Mother Fucker
(ii) My Friend

definition (i) is more commonly seen in chatrooms; whereas definition (ii) seen in multiplayer games.

if someone uses mf towards you, it's best to pretend you dont understand, so they will explain - either (i) or (ii). Since you dont want to just start insulting them.
<Shinosuke> Blah.. lets stop the conversation.. I dont want to talk abt it anymore.
<Person1> ok mf.
<Shinosuke> mf?
<Person1> mf - my friend.
<Shinosuke> Oh.. ok.. i thought.. nvm.
by Shinosuke May 13, 2004
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this word is used when youre tryna describe someone who hurted you so bad you can't even say his name. You call him "mf" short for mother fucker because he is the worst fucking person, he fucking played your feelings, he led you on, he made you fall for him, then he'll leave you with the "let's just be friends" so yeah fuck him.
Me: im boutta throw my goddamn hands on that mf
by realassbeach March 20, 2019
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