Most of these definitions are wrong.

Real piff AKA piffy is marijuana not laced, but grown with opium in it. Before the plant buds, a syringe is used to inject the choice opiate into it, thus the drug being distributed evenly through the plant. When smoked, the high produced by piff is more of a mellow, relaxed high, then the normal hungry/sleepy/happy/stupid high produced by marijuana alone.
I rolled a blunt with some piff I got from this dude I know, and I was so fucked up all afternoon.
by davis ave July 25, 2008
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A silent or hissing type gas passing, hence the name PIFF. Hands may be used to separate buttocks in order to achieve higher level of piffiness.

Originated in New Albany, Indiana. Brought to Southern California in the early 21st century.
"To avoid embarassment, Eric turned away from his girlfriend, discreetly spread his butt cheeks and let out a PIFF rather than a loud fart."
by Regnillo Girl June 16, 2009
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A word used for anything in general. Mostly known for drugs though.
"You smoke that piff?"

"That new sandwich at Mcdonalds is piff."
by Azurebaijan March 29, 2004
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marijuana laced with opium which gives it a better and stronger high
4 niggas gone off of one blunt of this piff
by mike j0nes November 29, 2007
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A very potent strain of marijuana. Mainly found in NYC. Its amazing high is due to the lacing of opium from a spray can and the original marijuana strain which is usually haze. "City Piff" is more potent then regular piff because it is sprayed twice with opium.
Yo I just copped that fire Buck-7-Duece Piff straight from the city.
by The UnderDose July 29, 2009
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weed in a bag, dat shyt ll hav u mookin 4 hourz
hell yea i smoke piff my dood
by Anonymous s.jeff set May 11, 2006
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