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An insult referring to the absence of wrinkles present in the human telencephalon(cerebrum) -- the largest region of the mammalian brain. Literally implying idiocy at a physiological level.
Those smooth-brained idiots voted for G.W. Bush twice!
by drastic_quench May 22, 2008
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Your brain doesn't work right and the gears don't function right. Otherwise said as you are stupid, dumb, an idiot.
Hey Darrell those eggs go in the fridge you smooth brained mother fucker.
by Smooth brained mf October 03, 2019
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