when a group of women live together or spend a lot of time together their monthly cycles tend to sync up.

or

when another woman on her period causes you to start your period early

(since women's cycles are often linked with the moon, it's not hard to make the leap from women's time of the month to werewolves and their monthly change)
I would have gone home with him, but my roommate "she wolfed" me and I couldn't.
by sovereigncookies July 14, 2011
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Lady in the streets, freak in the sheets. "She's a she wolf in your closet, open up and let her breathe," Shakira.
by Kay Cherie September 1, 2009
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A woman of any age, may or may not be amorous, who boldly and aggresively goes after men she find attractive in an almost predatory manner
"That she-wolf is after me, I think she wants to get in my pants"
by Moonbarker Osbourne August 10, 2007
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We are legendary. You've heard of us.

Native to Hingham, the She Wolves rule the world, specifically the Patriot League Cross Country world. They are amazing in every way and almost godlike. They run faster than the wind and ravenously devour pizza on Tuesday nights. You want to be us, but you are not us.
She Wolves are the only inhabitants of the Earth described accurately by the word perfect.
She ran with the strength and endurance of a true "She Wolf"
by marshjoel December 13, 2009
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The mother of all that is evil
Her lips are poisonous venom
Wicked temptress knows how to please
The priestess roars, "Get down on your knees"
Beware what stalks you in the night
Beware the She-Wolf and her bite
Her mystic lips tell only lies
by FFFFUUUUF October 29, 2011
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A woman capable of going after numerous guys (single and taken) while completely disregarding their emotions or reactions to her actions.
Alice told you she's fucking some other guy even though you're taking her to prom?! What a she-wolf.

Dude, Ian's she-wolf is here, and she's totally caking on drummer Joe.
by Smat McSplandt April 20, 2009
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A super hot, blond, bellydancing, Colombian pop star that sounds like she is yodeling all the time.
SHAKIRA!!!
ex. 1.) Rosie: Oh mah Gawd, I am totally not a Lesbian but that Shakira is such a She Wolf; she can bite me anytime.
ex 2.) Jeffery: Yanno I am not heterosexual but it would be fabulous if Shakira were to bite me too with her fierce She Wolf self.
by Lycanthropiachic December 20, 2009
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