reggie mayne Share definition Flag Reggie mayne is a human of low quality. They are below average. It can also be referred to as low quality marijuana. Ex: that weed is garbage. That's some reggie mayne schwag.Ex: fuck that kid, he's reggie mayne. reggie mayne by b4younewit March 11, 2015 0 0 Get merch Get the reggie mayne mug. Buy Now — $32.95 See more merch