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pneumanoultramicroscopicsilicovolcanoconiosis 

The longest word in the English dictionary. It is a type of pneumoconiosis, a lung disease that one can get from breathing microscopic volcanic ash. It was a word invented in the early 1900s specifically to be the longest word in the English Dictionary. Since then it has been published in various well-respected dictionaries.
Doctor: I am sorry to say that you have pneumanoultramicroscopicsilicovolcanoconiosis....

Patient: ....................... can you spell that for me?

Doctor: um..... P... N.... O...EGIUHAEIHPIUHERPIUHGPIUHEAPIGPWEYGBJROIUPQUYPHIAUHF
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pneumonoultramicroscopicsilicovolcanoconiosis 

An inflammation of the lungs caused by microscopic grains of certain types of rock.

*NOTE* This word was actually coined in a deliberate attempt to be the longest word in the english language, although you would be hard-pressed to find it in the language dictionary as it is a medical/scientific term.
"Dude, now that I've learned how to spell antidisestablishmentarianism, what am I going to do to make people think I'm smart?"

"Quiet man, I'm trying to name this condition we discovered today. Its an inflammation of the lungs caused by microscopic grains of certain types of rock."

"Hey, I smell opportunity! How long could we make this word?"

"Pretty long...I suppose we could stretch it to pneumonoultramicroscopicsilicovolcanoconiosis"

pneumonoultramicroscopicsilicovolcanoconiosis 

A: What's the wifi password?
B: It's on the back of the router.
The router: pneumonoultramicroscopicsilicovolcanoconiosis

pneumonoultramicroscopicsilicovolcanoconiosis'd've'ly'yaint'nt'ed'ies's'y'es'nt'ed'ies's'y'es'nt't're'ing'able'ric'ive'al'nt'ne'm'll'ble'al 

the longest possible grammatically correct EVER.
man i really pneumonoultramicroscopicsilicovolcanoconiosis'd've'ly'yaint'nt'ed'ies's'y'es'nt'ed'ies's'y'es'nt't're'ing'able'ric'ive'al'nt'ne'm'll'ble'al ing hate this guy

pneumonoultramicroscopicsilicovolcanoconiosis 

1. A disease gotten from inhalation of diminative particles of silica or quartz.
Pneumono - Lung
Ultra Microscopic - Very small/fine
silico volcano - igneous, silica
coniosis - disease
; Black Lung
In the mid 1880's, miners would get pneumonoultramicroscopicsilicovolcanoconiosis.

pneumonoultramicroscopicsilicavolcanoconiosis 

The longest word in the English language.

A disease of the lungs aquirable by the inhalation of silica dust.
Dude! That guy was diagnosed with pneumonoultramicroscopicsilicavolcanoconiosis yesterday. What a bummer!

pneumonoultramicroscopicsilicovolcanoconiosis 

A form of silicosis caused by breathing in siliceous volcanic dust.

Exceeded electrophotomicrographically as the longest recognized word in English.
Me: *COUGH*
You: Dude, stop smoking.
Me: I don't smoke.
You: Yes, you do.
Me: No, I have pneumonoultramicroscopicsilicovolcanoconiosis