Basically a "shot glass-sized" cup filled with a concoction of pills, most likely prescription pills, that a person consumes in one sitting.

Kind of like when nurses at hospitals hand out a patient's medication in those little paper dixie cups, then they shoot the pill(s) to the back of their throat as if they're downing a shot of tequila.

Addicts or people who think they need a pill and/or vitamin for everything, would be known to devour pill shots regularly & voluntarily at home. Old and/or seriously sick people with multiple prescriptions usually have to prepare pill shots as part of their daily regiment instructed by their respective doctors.
Lorraine has to make sure her mentally unstable niece Suzanne actually washes down her nightly pill shot of antipsychotics, otherwise her behavior can become unpredictable & dangerous.

After his divorce and car accident, Mike eventually became addicted to taking a pill shot of Vicodin tablets every night to help numb his pain, far more than the doctor's recommended dosage. He eventually ended up in rehab but recovered successfully.
by THEjoseG August 13, 2014
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