when an orgasm is so good you immediately fall into a state of semi-conscious hallucinogenic bliss.
"allison's peyote orgasm was so good she started muttering something about lizards and numb feet."

or,

"hey, what happened... did i black out?"

"no sweetie, i just gave you a peyote orgasm. and now i know how you feel about dancing grapes."
by polarpig October 06, 2009
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Someone who leads you on a fantastic, most likely impossible and quite possibly fatal drug-induced quest for more drugs.
When I was down in Mazitlan we scored some good weed from these German tourists that were staying at the resort with us but it wasn't enough for Erik. He started asking some Mexicans about getting some coke, we got on the back of some guys Motorcycle, drove out to the middle of nowhere in the middle of the night and behind the shadiest bar I've ever seen he scored a bag but we are lucky, and not that I'm not grateful but that could have gone bad. Really that Don Peyote is going to get us killed some day.
by Sancho's Panther August 10, 2008
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A human being so repugnant that no amount of mind altering substances could possibly make them attractive.
That girl is Peyote Ugly.
by Jburkett85 September 18, 2011
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Sam: Hey, can I borrow $50?
Eric: Uh, I loaned you $200 last week. No. You and Phil Jackson can go smoke some peyote.
by ChuckChaser69 May 08, 2011
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from the earth, when consumed brings oneself closer to earth
while on peyote;
the white man goes to church and prays to god,
the indian goes to his temple and speaks with god.
by Sole 8676 November 09, 2021
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Slang for cocaine; originated in Jackson Hole, WY.
Man, those vodka red bulls are kicking in. I just talked to my wife and she said I was cool to party, let’s get some white peyote and take this to the next level.
by The Deep Safety July 03, 2019
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