A word to express when you know what you are attempting will not be successful.
Man 1:Hey dude do a backflip!

Brady: *attempts backflip* nope! *lands on neck*
by Cdawgie October 25, 2008
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A response to something that you want no part of.
Guy: (plays a YouTube video only to realize a moment later that it's a gross medical documentary) Nope!
by Ash-Greninja December 30, 2016
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A playful way of saying no.
tyler: are you drunk or something?
jed: nopes.
by sfjedi January 7, 2009
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The ultimate vocal response in Team Fortress 2, spoken by the Engineer. A single word so powerful that not even the greatest RAGE or trolling can counter its effects.
1)
Player A: We'd probably be winning if we didnt have 5 engies building shit at the spawn

Engineer: NOPE

2)
Disgruntled player A: RTV! NOMINATE! SCRAMBLE! This map sux111!! Youre all using HAX!!11!

Engineer: NOPE
by Zeromus255 October 4, 2011
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-To deny your ability to perform physical activities
-to bail out
-to fail
Boy1:OK, Brady you can do this back flip!
Brady: Well, okay...Okay guys!
Boy2:DO IT BRADSTAAAAAAH!!!! I'm filming!!!
Brady: I can do it!
*halfway through back flip*
Nope!
*falls on neck*
All: *hysterical laughter*
by 13333333337gangsta February 23, 2009
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The new generations response to drug use. NOPE to DOPE. Showing an attitude of being disgusted with dope does. It's owning better choices for yourself.
NOPE! Noway I would poison myself with drugs!
by jesRika December 26, 2019
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