To know someone in the biblical sense means that you have had sexual intercourse with him or her. It is a reference to the meaning of "know" in the Bible.
Man 1: What do you mean by "know in the biblical sense"?
Man 2: I've slept with her. We dated last year.
Man 2: I've slept with her. We dated last year.
by A1988 December 12, 2012
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