It is used to name female people that are really close to you. It means Sister.
Hola hermana, que pasa?

Hey sister, whats up?
by spanishsteve February 23, 2009
When your doing a Mexican girl and you use hot sauce as lube and as you pound her she screams like that of an Mexican Hermana Singer.
I think I'm going to Mexican Hermana my gf because she is Mexican.
by Cuckshed438 January 8, 2021
Un hermano o hermana de pierna es cuando dos personas han tenido algún tipo de relación subida de tono con la misma persona, se han comido a la misma persona o han tenido relaciones sexuales con la misma persona.
Con la Sofi somos hermana de pierna porque las dos nos agarramos a Joaco
Sofi and I are hermanas de pierna because we both make out whit Joaco
by marianita August 2, 2020
All he said was "Mi Hermana."
by Fiery Shadow June 4, 2019
Thick and Juicy, a women who just makes you believe that Moses himself would've given his life for her
Did you hear that angel? Hermana Sandra hekn thiccc
by Slick Boi December 30, 2017