In online role-playing games. Spending countless hours killing enemies to level your character.
Perry: "How'd you get to level 40 in one night?"

Nathan: "You just have to stay up and grind it like all night.
by desperryado November 26, 2005
Get the grind it mug.
When you’re working your ass off to get somewhere!!
-you know me always at the gym trying to get that sexy body. Grind grind grind!! 🔥
-damn my sister working so hard at school getting that grind grind grind!! 💯
-working night and day for that paycheck yes you go bitch GRIND GRIND GRIND!!🔥
by sexymonster244 January 15, 2018
Get the grind grind grind mug.
when you work your ass off to get shit done
Dini: Have you started working on college apps yet? The deadline is in four days.
Gabby: Not really, I haven’t started any of the essays yet.
Dini: Shit, you’ve gotta grind girl!
by ur b1tch October 28, 2019
Get the grind mug.
staying "on the grind" means to work hard, always be hustling, or otherwise engaged in money-making or woman-procuring activities.

people who were once poor and become wealthy might then become lazy and indolent and spend all day in champagne-filled jacuzzis whereas other newly-successful people might continue to work hard, thus "staying on the grind"
there are many examples from 50 Cent's latest release, "the Massacre", but i'll offer up two:

excerpt from "God gave me style":

A O.G. told me God's favorites have a hard time
You out the hood, that's good now stay on the grind


Chorus from "Bitch get in my car":

I got no pickup lines
I stay on the grind
I tell the hoes all the time
Bitch get in my car (Bitch get in)
I got my 64, ridin' on Dayton spokes
And when I open that do'
Bitch get in my car
Get the on the grind mug.
When you're working hard either at work or at a job.
Charles is grinding at work today.

Grinding trying to get that paper.
by tutie411 September 24, 2018
Get the Grinding mug.
Also Known As Dirty Dancing. When a girl is rubbing her ass all over a guys dick until it comes to the point where he gets a woody
i was grinding with this girl with the biggest booty
by ___ October 19, 2003
Get the Grinding mug.