To fire one off is to take a crap.
I hadn't crapped for a month, until I couldn't hold it in any longer and I then just fired one off.
by OliverS May 7, 2005
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My bitch wasn't around and I was hornier than a dog with two dicks, so I quickly fired one off the cuff before she came home.
by Absintheminded April 9, 2004
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