Complex protein system capable of re-arranging genomes (DNA) by means of its Cas9 endonuclease (RNA guided, restriction enzyme) it has the capacity to be programmable and will be a major influence in the next decade or so.

Crispr has been used in trials to reduce the % of cancerous cells in mice from 99% to the lower 40s, all by sheer efficiency.

crispr by BurpFartVaginaFaceTheIV March 14, 2017

Crisper Gang

A Tight gang who feasts off of rice crispy’s and they logo is a snake

Wow dude I got excepted to the Crisper Gang

Crisper Gang by Crisper Gang January 13, 2018

CRISPR

"Clustered Regularly Interspaced Short Palindromic Repeats."

The word "CRISPR" is an acronym that stands for "Clustered Regularly Interspaced Short Palindromic Repeats." It was coined by Spanish microbiologist Francisco Mojica in the early 2000s. Mojica was studying the unique DNA sequences he had discovered in certain bacteria.

The name "CRISPR" is descriptive of the key features of these DNA sequences:

Clustered: The sequences are grouped together in clusters.
Regularly: They are found at regular intervals in the bacterial genome.
Interspaced: The repeating sequences are interspersed with unique DNA sequences.
Short: The repeating sequences are relatively short.
Palindromic Repeats: Some of these repeating sequences exhibit palindromic properties, meaning they read the same forwards and backward.

Mojica's discovery of these unique DNA sequences laid the foundation for the development of the CRISPR-Cas gene-editing technology, which has since become a revolutionary tool in genetics and biotechnology. While Mojica coined the term "CRISPR" and made significant early contributions to the field, it was subsequent researchers, including Jennifer Doudna and Emmanuelle Charpentier, who adapted and applied CRISPR technology for precise gene editing, earning them the Nobel Prize in Chemistry in 2020.

"Scientists are using CRISPR technology to explore potential treatments for genetic diseases by precisely editing the DNA of affected individuals."

CRISPR by Chief Lexicographer October 4, 2023

nigger crisper

Flamethrowers equipped to sides of South African cars to prevent theft.

Okonkwo tried to steal a car and ran into a nigger crisper. That nigger got crisped.

nigger crisper by NiggaPleez September 7, 2006

You met me at a very Chinese time in my life

A moment in time where you feel distinctly Chinese over all other things.

Dante: "I wish I could be Nigerian, but I can't because I'm Chinese. You met me at a very Chinese time in my life."

You met me at a very Chinese time in my life by Sus Chad September 21, 2026

Word of the Day on September 25, 2026

crunchy

Adjective. Used to describe persons who have adjusted or altered their lifestyle for environmental reasons. Crunchy persons tend to be politically strongly left-leaning and may be additionally but not exclusively categorized as vegetarians, vegans, eco-tarians, conservationists, environmentalists, neo-hippies, tree huggers, nature enthusiasts, etc.

Also used to describe establishments where alternative foods and products are sold, i.e. natural food stores.

Modified derivative of granola.

"I need more crunchy guys in my life. I'm so tired of dating preppy metrosexual assholes."

"I'm heading out to the crunchy store to pick up some fair trade chocolate and tea tree oil, do you need anything?"

crunchy by EBC July 11, 2007

Word of the Day on September 24, 2026

Galantir

A group of people, typically women, searching through someone’s digital footprint in order to find more information about that person.

Susie wasn’t sure if her new Hinge match was a creep, so she assembled Galantir and they found out he used to post slurs on gaming forums.

Galantir by Ge-sus September 22, 2026

Word of the Day on September 23, 2026

murderhobo

In a tabletop game, a murderhobo is a player who murders NPCs indiscriminately. This is normally derogatory, referring to a player who totally ignores quests, dialog, backstory, trade, world building etc.

The term is most common with Dungeons and Dragons, but it can be applied to most RPGs where the player is allowed to kill most quest-giving NPCs and NPC traders. E.g. Elder Scrolls, Fallout, Divinity original sin.

DM: The sad little orphan girl tugs at Steve's trenchcoat to get his attention, and ask for help saving her pet dog from...
Steve: I'd like to roll a strength check against strangling the orphan.
Dave: I call dibs on the dog.
DM: You murderhobos disgust me.

murderhobo by Loup&S September 9, 2021

Word of the Day on September 22, 2026

Whale

In sales terms, a whale is a prospect that is significantly larger than an organization’s average customer.

Whales are large and extremely difficult to close. Due to their immense size, they are highly sought-after.

A whale is typically identified at first by a whale hunter on the sales team, but often requires cross-discipline participation in order to close; this includes assistance from operations, engineering, creative, client success, and business development teams.

"Shit...the sales director chewed me out on the sales call this morning. He's totally pissed that I have nothing in my pipeline. I've been focused on this one whale for so long that I haven't had time to prospect for normal-sized deals."

Whale by FQ_GFY February 3, 2020

Word of the Day on September 21, 2026

Concrete cowboy

A guy who thinks he's a country kinda guy, but in reality lives a comfortable city / suburban life.

Eugene: Look at that dude in the cowboy hat!
Todd: He's just a concrete cowboy.

Concrete cowboy by EugeneJohnson42000 March 16, 2024

Word of the Day on September 20, 2026