Name givin to reference the northern suburbs of Ephrata, PA. Technically this area is divided up into East and West Cocalico Townships. West Cocalico is more sparse & detached while East Cocalico Township is one of the larger townships in Pennsylvania.

Cocalico is known to be a generally boring place. It's major commercial hub Denver, Pa doesn't even posess a grocery store. The older residents of cocalico are generally intolerent people who dislike minorities and go to the local vfw 4 days a week.
"Ephrata wasn't gay enough for my family, so i decided to purchase a home in East Cocalico."
by crackCAT$ May 31, 2009
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A particular form of gonorrhea, established in cocalico, PA. The term clap comes from the popping of puss pockets in sexual organs.
-Yo I think I got the cocalico clap...

-Poor guy, I told you to stay away from Irene!
by cocalico hero November 30, 2006
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Cocalico Middle school is where you will find all the gay people and it is hell really people be crying and pissing their pants
Cocalico Middle School is very gay. And so is Ephrata
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Cocalico is home to the biggest community of jocks, vape lords, and Denver thugs. They like to spend their time smoking, partying, or cheating during a test. Most people end up staying in Cocalico and doing nothing with their life. It is located in Lancaster, PA.
Hello do you go to Cocalico High School? Have any beer?
by nobodylonerweirdonerd March 21, 2021
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The coolest high school ever with the awesomest students ever. the coolest people come from cocalico high school. cocalico high school is in the northern part of lancaster, PA
Cocalico High School class of 2011 are the hottest people alive.
by amishfolk October 14, 2010
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Cocalico Middle School is the amalgamation of cis boys, gay people, and suicidal children - a hellscape where one shall be bullied no matter who they are, and being anything but able-bodied, cis, hetero, and white will get you made fun of.
I love the teachers at Cocalico Middle School, but the kids suck ass.
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