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Automated gameplay. Generally by using programs to play games for you.
Bob: What's up?
Me: Botting for D2, hold on.
botting by Willum September 2, 2006

cross-botting 

Using bots (typically Discord bots) outside their designated channels.
Norbert was cross-botting the Pokecord bot by using it in the Music bot channel. What a naughty pineapple!
cross-botting by airswidjaja April 1, 2020

the Botting 

An amazing beverage native to Grove City, PA. The Botting is 1/6 100 proof Rumple Minze Peppermint Schnapps, 1/6 100 proof Captain Morgan's, and 2/3 Dr. Pepper.
Dude, I hear that you can order the Botting at the local bars!
To stop liking someone when you find out they like you back. vice versa.
Sally: He told me he liked me... I don't think I like him anymore.
Jessica: Sally! You're totally botting!

Jack: Once I told her I liked her, she ran away. She is such a botter.
botting by yeeting247 December 18, 2015
Programs used to cheat in games. (A.K.A. Being smart about playing a game...all the skill/stats of a pro no lifer...and you get to keep your life!)
Nerd: OMG almost level 99!21ononeone!!111!!
Botter: Bro, I'm botting and I'm on my 3rd 99 P;
Nerd: Reported!
Botting by Phr33Pls January 13, 2010

runescape botting 

The process of using bots to gain gold, Real Life money, or stats in the game. Best thing ever to do in runescape can make 500+ a month doing it.