Man, I wish Johnny would ask me out." "Don't count on it, he's suffering from the Alyssa Effect.
by imreallyannoyedwiththis December 16, 2010
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Turning previously normal straight women into horny e-lesbians who call her mommy.
I just experienced the Alyssa Effect and now I just can't stop calling her mommy.
by m0mmymymymy January 30, 2022
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the effect of being annoyed, pestered or just plain pissed off by someone who constantly brings up high school stories or talks about their high school friends. rooted in college dorms where one person clings on to their old life instead of meeting new people.
You wanna go out to a party with the girls in 421 tonight?

No way man, they got the Alyssa effect goin on in there, Mary just won't shut up about her friends at home.
by they call me tater salad... October 22, 2010
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The Alyssa Effect is a cycle where the partner in question end their relationships saying they aren't happy and the "significant" other needs to activate conversation, they do this with multiple partners to where it's a cycle, hence the the Alyssa Effect
Dude this girl I'm dating is undergoing the Alyssa Effect.
by Issac_Newton22 October 17, 2023
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