To completely ruin an event, outing, or something in particular for many people.

Derived from John Lennon's girlfriend who broke up the Beatle's and ruined their music for the entire world.
Jim forgot to get a keg for the party and Yoko Onoed the entire night for everyone.
by cml003 December 8, 2013
An influential woman who provided John Lennon with inspiration to write some of his most beautiful live songs, like “I Want You (She’s So Heavy) She is the second half to a love that was so pure, and passionate, even until the end.
I want you
You know I want you so bad, babe
I want you
You know I want you so bad it's driving me mad
It's driving me mad

(About Yoko Ono)
by Swaybe April 7, 2006
A person that is loved so much, one would give up anything to be with them, as sang about in the Barenaked Ladies' first hit, "Be My Yoko Ono"
"...I would gladly give up musical genius,
Just to have you as my very own personal Venus.
You can be my Yoko Ono,
You can follow me wherever I go,
Be my (be my) Be my (be my) Be my Yoko One, Ohhh-Oh."
by Pork King December 19, 2005
Yoko Ono is considered one of the most important characters in The Beatles history.

Yoko comes from an affluent and influential Japanese family. It is rumored that Yoko's great grandfather had amassed a fortune of a billion dollars by his assassination in 1921.

Yoko studied at the same school as Emporer Hirohito's two sons, where she became heavily interested in the arts. However, she dropped out of Gakushuin University and at the age of 20 she enrolled at Sarah Lawrence College - coincidentally the same college that Linda Eastman, future wife of Paul McCartney attended.

Yoko began touring as an artist, and appealed to the artsy upper echelon of New York and Tokyo. (In 2002, Ono wrote that at the time she thought herself avant garde - a real talent, but she now realized that she was a nobody in the scheme of things.)

Yoko's had her first child, and second marriage, with Anthony Cox. They traveled playing music, and shooting short films. One of their more memorable works is of the striking of a single match. Another, was their 1966 film 'Buttocks,' in which they traveled to London to film 365 Briton's naked backsides. Notably, a journalist named Hunter Davies was invited down to the shoot, and devoted his column to the story "Oh no, Ono!", which introduced the British Public to the Japanese artist. Notably, Davies went on to write the The Beatles' first authorized biography - spending endless of hours with the band during the Sgt. Pepper's Lonely Hearts Club Band recordings. Davies can be seen in the 1967 All You Need Is Love / Baby You're a Rich Man TV performance.

Yoko Ono met John Lennon, singer/songwriter of the The Beatles at an exhibit of her work at the Indica gallery in London. However, it was not until the Yellow Submarine world premiere in 1968 that the world saw them together for the first time. They soon became inseparable, their togetherness even intruding into the The Beatles' recording studios, a place that until then had been a band-member only sanctuary.

Yoko quarreled with the band, even with producer George Martin during editing stages. Nonetheless, the couple stayed strong. Both John Lennon and Ono divorced their spouses. (Interesting note - John Lennon's elation in hearing Ono's successful divorce was caught on tape during an early run through of Paul McCartney's "Oh, Darling!", which can be found on the The Beatles Anthology 3 album.)

The marriage of John Lennon and Ono was chronicled nicely in John Lennon's #1 single The Ballad of John and Yoko / Old Brown Shoe The ballad tells the story of the public's outcry against their beloved John Lennon marrying Ono, and their struggles to find a place to wed. This song was recorded solely by John Lennon and Paul McCartney, John Lennon on lead vocals and guitars, Paul McCartney on backing vocals, guitar, bass, and drums.

The Beatles disbanded at the end of the decade, and each of the members went their own ways. John Lennon embarked on a sadly short lived solo career, and he did this hand in hand with his Yoko Ono.

Yoko Ono was ever-present in John Lennon's work, being mentioned in nearly every song on the John Lennon/Plastic Ono Band and Imagine albums. The two continued to make music together (besides a break-up in the mid 70s, but this was hushed up), up until 1980's Grammy winning Album of the Year Double Fantasy.

John Lennon's story ended that year with his assassination outside his New York apartment. Yoko Ono has been slandered as a professional widow, and the woman who broke up one of the biggest bands of all time. True or not, she is an icon of the 60s and 70s, and a reminder of a part of music history.
by Geoff L. August 5, 2005
Second wife of John Lennon. Often blamed for the break-up of the Beatles when infact she just happened to be there. This is called yoko syndrome
by Gumba Gumba February 24, 2004
the action of one's significant other who tears apart the group of friends.
"Dude. Adam never hangs out with his old friends anymore."

"Yeah. Once Susie came in she just started Yoko Onoing the shit outta them."
by Phil Jacklin October 7, 2007