What is up? 

The way you greet a friend when you are feeling a little bit retro and a little bit geeky.

What is up my brother?

What is up? by Anonymous August 18, 2003

What is up? 

Asks what another has his attention on. What is he thinking about or busy with? "Up" in this case is using a slang definition from around the 1930s meaning: occupied with, busy with.

This question is often used to start conversations with.

When I called my friend he didn't seem happy so I asked him "What is up?". He said he was having trouble with his girl.

What is up? by Scottmana September 29, 2007

What is up with that

What you say when you do not really know what to say.

Bill: "hey look at that"
Ted: "what is up with that"

What is up with that by nellaws September 24, 2003

what is up chappy?

Phrase often used by those alien to slang.

big earl:YO mofo
Harry: What is up chappy?

what is up chappy? by the village people June 18, 2006

Hey What is up Guys It's Scarce Here 

The intro to youtuber Scarce's videos.

The phrase is sometimes used by hackers to make people think Scarce hacked someone.

"Hey What is Up Guys It's Scarce Here" has been said so much it has become a meme.

Hey What is up Guys It's Scarce Here by TheYellowAmpharos October 24, 2016

Tell Me What Is up SOme More 

Tell Me What Is up SOme More

Tell Me What Is up SOme More

Tell Me What Is up SOme More by SuelTameOresuTeMato April 25, 2025

what is you up to 

An expression commonly mistaken with "what's the haps", What is you up to is the complete opposite. The expression simply means to wonder as to what activities another individual is partaking in at any given moment.

brotha:YO, what is you up to
hommie:just chillin with some peeps.
brotha: fly!

what is you up to by SLICK MOTHA May 3, 2006