1. Marshmallow, in a jar.
2. Part of the ingredients in Jane Rizzoli's favorite type of sandwich fluffernutter
Maura: What is this white substance?
Jane: Fluff.
Maura: Light, downy particles of cotton?
Jane: It's marshmallow, and the brown substance is called peanut butter. It's ground up, heavy, oily particles of peanuts.
by msanimanga August 3, 2011
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"Fluff" is a term for acid that is made by the Grateful Dead Family, also called "family fluff."

Usually decent, sometimes good.

Depends on your location, but you should never pay more than $10 / hit...
"Hey what's up"
"What have you got lately?"
"I got the regular and I got some doses, family fluff"
"Oh word?"
by Rinn17 February 11, 2010
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Means to fluffle someone when typed in by someone who cant spell fluffle (see seperate definition of the corretly-spelt fluffle for examples)
Morthy fluffes Joe|away
by Vin Rhinocelot February 28, 2005
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"Fluff you are the most magical of all the beings"
Makes sense when said by someone referred to as a snail
by 🐌♥️🐻 November 13, 2019
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Mary let go of a huge fluff in the staff meeting today.
by GarretK November 14, 2016
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An abbreviation for "marshmallow fluff," a gooey white substance mainly used as a sandwich spread. Can also be used in place of marshmallows for baking purposes. Often made into a contraction with peanut butter as "fluffernutter," a combination of the two sandwich spreads on bread.
Hey, pass me that jar of fluff, Karen!
by aytheist April 16, 2004
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