Any non-specific malady affecting one's ability to interact under the rules of normal social contract.
There is something off with that dude. Everytime I leave a conversation with him I just don't feel right. He's got some sort of tism.
by JungleKitty November 14, 2014
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That random ass hoe Joe (Joehoe) is hardcore tism with his grapefruit lookin ass
by Seeeee the future March 15, 2017
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Lucy is having a tism and therefore won’t be able to make it to the party
by shishish June 25, 2018
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T.I.S.M. (This is Serious Mum)

An Australian post-modern band. They take the essence of being Australian to a whole new level.

The best example is the song "The parable of Glenn Mcgrath's haircut"
Don't leave your sister and Tism in the same room.

"I saw his body thrashing round,
I saw his pulse rate going down,
I saw him in convulsive throes,
I said i'll have one of those."

Lyrics "He'll Never be an old man River"
by H.B. Flaubert September 29, 2005
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A bunch of alcoholic child-beaters. Coincidently, they make music.
Tism abused my son, but their new CD is pretty cool.
by Ya Mum July 12, 2003
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Describing someone who messed up a lot, or can't speak correctly. This person can just be a mess. Tism is characterized by difficulty in communicating with others, or just being unreliable.
by samibitt January 10, 2018
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