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To make a typo while inputting text on a hand held device such as a cell phone.
"Hey guys, gow ard yot?"

"Sorry, I mean, how are you? Whoops, looks like I thumbled!"
Thumble by HTCS July 7, 2009
A portmanteu of thumb and stumble, works best when used with up or down to signify delight or disgust about a page using the Stumble Upon toolbar.
"dude, shit's cash, thumble up"

"ewww, no more Nailin' Palin for me, thumbled down"
Thumble by Danliv2003 March 19, 2009
When your girlfriend texts your wife thinking it's you. like Bret Favre or Tiger Woods.
Thumble by lyradius August 14, 2011
portmanteau of Thumb and Rumble, a slang word purportedly used in online gaming.

Seen in a badly researched episode of CSI, where a fat gamer is murdered
"Whenever he's bored, he just goes online. there's always someone looking to thumble"
Thumble by NanakoAC February 19, 2013
A poke at the 16 years it took Tom Brady's dynasty to fall, 1/19/02-1/19/18

R.I.P.
In 2018 before the AFC Championship, QB Tom Brady injured his thumb, social media blew up and took to the name THUMBLE. This is where the word came from.
*stubs thumb on lightswitch*

Mom: THUMBLE!!
Thumble by FunnyWords23 January 19, 2018
To stumble upon something while one is thumbing through a book or some form of media.
She thumbled upon a picture of her younger self from 2002.
Thumble by anonymous April 30, 2022