Stinky Sack Syndrome Share definition Flag When your nutsack is so dirty/sweaty that you can smell the stench. Edward had a bad case of stinky sack syndrome after playing Gamecube for 5 hours. Stinky Sack Syndrome by Clickety Clack Productions October 18, 2008 0 0 Get merch Get the Stinky Sack Syndrome mug. Buy Now — $32.95 See more merch