When one eats spicy food, and the next day he or she has a burning feeling in their intestines
Brad: Hey, Chipotle was pretty fun last night!
Angelina: FUCK NO!!! It gave me the worst spicy butthole ever!
by Rancid Weiner March 13, 2011
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to bust a nut in someones ass of to urinate in it
Joe : Damn bro jail got me fucked up
John: what happened
Joe : i dropped the soap and got a spicy butthole
John : are you okay
Joe : no i have an infection and it hurts
by yourmommakesmewanttobeyourdad September 27, 2018
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When you consume spicy foods and you feel like it's not gonna come out good later.
I'm gonna have spicy butthole disease later.

Or

I have spicy butthole disease.
by ghostlypeachess February 13, 2020
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