bf "I learned something new on the Spice channel."
gf "really show me..."
by mr. filler July 15, 2004
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2-CI, aka 2,5-dimethoxy-4-iodophenethylamine, a short acting synthetic psychedellic compound. Can be taken orally or snorted.

Often confused with mescaline, therefore it is sometimes refered to as "synthetic mescaline".

the name comes from the fictional conciousness expanding drug "spice" found in the book Dune, by Frank Herbert and the Star Wars films.
"They have been tripping on the spice all night."
by they speak to me in dreams October 17, 2005
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Hot, good looking individuals, usually girls.
John: "Where's the spice at tonight, man?"
Mike: "The group of blondes that just walked in."
Alex: "I'm going to find me some spice tonight."
by Laurp November 9, 2007
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A word used in Connecticut to say someone is ugly as hell
Girl 1: you see that girl ova there
Girl 2: yeah

Girl 1: she Spice af!
by LadyGlitterSparkles24 June 23, 2017
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The plural of spouse.
When talking to my friend I ask, "should our spice come along, or should we leave them at home to do dishes?"
by throwhimdownthewell October 6, 2006
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English: Spice, French: épice
Used also as slang originating from the Guinean dialect of French and also sometimes spoken in English by natives of Guinea Africa and other french speaking countries of the Ivory Coast.

-As slang it is used to mean a person who gets into things, situations and relationships and ruins them.

-A person who annoys or bothers others.
That guy is spice to this whole group, he has got to go.
by Mr. Snowman pants July 25, 2010
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A synonym of cool, lit. When something’s spicy (not flavor)
That’s spiced. Eso es especiado. His shoes are spiced.
by Kalin808 November 2, 2018
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