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significantly 

1. a. Having or expressing a meaning: Are the markings on the stone significant?

b. Having or expressing a covert or nonverbal meaning; suggestive: a significant glance.

2. Having or likely to have a major effect; important: a significant change in the tax laws.

3. Fairly large in amount or quantity: significant casualties; no significant opposition.

4. Statistics Of or relating to observations or occurrences that are too closely correlated to be attributed to chance and therefore indicate a systematic relationship.
The left rock was significantly larger than the right rock.
significantly by Foxy-Toes January 2, 2017
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Significantly Better Class Newspaper 

A Hilarious post that is a tad bit offensive, and makes fun of the teacher.
person 1: hey, did you see the Significantly Better Class Newspaper?
person 2: yeah, it was really silly.

significantly otherwised 

Involved in a long term romantic relation..coupled (singular form)
I am not significantly otherwised so I'm free to make plans for next weekend.
significantly otherwised by mj57 September 28, 2013

significantly anomaly 

An obvious dicrepance
Significantly anomaly is resultant contributed to various factors.

Significantly refreshed 

To be intoxicated on a large amount of alcoholic beverages.
Due to the open bar the wedding guests were significantly refreshed and dancing like drunken baboons.

significant sasquatch 

The feral countenanced beloved of a friend who, due to body or facial hair, appears more sasquatch than human.
Ex. 1: Though Jen loved Mike, she was certain that her friends perceived him only as her significant sasquatch.

Ex. 2: I have it on authority of an expert that the perfect gift for my significant sasquatch is a pig ear.
significant sasquatch by Malazoth November 18, 2010

significant other 

Your mate, spouse, husband, wife, boyfriend, girlfriend, steady and/or lover. Used when you don't want to be too specific, or when the details are nobody's business.
Why's Roger always talking about his significant other? Why don't he just say girlfriend?

Because his "girlfriend" is a guy named Bruce.
significant other by Alex Firmament February 20, 2009