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A word often used in exasperation, when there is no hope of continuing. Often this word is used when an argument has been lost, or when someone is, metaphorically, out of cards. Synonymous with "I'm pissed off that I've lost this argument, and this is the only intellectual retort I can muster".
Hayden: I fucked your mother, bought all of your stock, and burned your house down.

Greg: Shutthefuckupious
by SirFrye December 02, 2013
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