spleen 

The internal organ that is invariably complained about when someone is comedically getting the shit beat out of them.

"Oh God, my spleen! It hurts! It hurts!"

"My spleen has ruptured!"

spleen by Morathor March 30, 2004

spleen 

An internal organ of the human body on the left side.
It's job is to destroy old red blood cells.

My spleen is destroying all those old red blood cells, RIGHT NOW.

spleen by elissanozit April 23, 2009

spleen 

an internal organ most widely known for "cleaning shit and stuff".

"Every kitty needs their spleen."

spleen by LovesSomeKitty April 30, 2009

spleen 

1)When one has nothing to say except complain about something - the spleen.
2)When something hurts.
3)A word that can be used when referring to almost anythung. Like that of meh.

1)*groan* ooowwww.........my spleen!
2)My spleen hurts, well something hurts,...it must be my spleen.
3)person1: whats her name again?
person2: ah, spleen!

spleen by G-UNIT March 15, 2005

spleen 

Where something spleens over the ground, similar to the action of a water balloon hitting and bursting on a surface

You trip, you wurzle in the air, and you spleen all over the ground

spleen by BenKenTheBest April 4, 2003

Spleen 

Considered by some to be a godlike being.

"why are you so obsessed with spleen?"
"Spleen"

Spleen by Bigmoris April 21, 2021

Spleen 

Slang for a hard working, good quality organ.

Man 1: "Hey man, you still on the waiting list for that transplant?"

Man2: "Yeah dawg, I'm holding out for that spleen."

Spleen by DoubleCrissp November 13, 2022