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Area of sensation around the anus, supplied by the 5th sacral nerve, or S5. Also can be used in reference to anal sex.
My girl finally gave up the S5 last night, and it was fuckin' awesome!

I let my boyfriend have my S5, and I came so hard when he did.
S5 by lola time August 7, 2007
Related Words
S5 means Shiesty 5 and slimey 5
Aye you heard about them “S5” boys ?
Yea they dropping shii
S5 run nikkas , S5 also like upping the score , S5 be staining shxt , S5 run these nikkas
S5 don’t got opps it just a group of hating ahh nikkas dat done like them
“S5” be beating shxt

“S5” be making nikkas fold
“S5” run shxt
“S5” got them Fans scared
S5 means SOCKS 5 A SOCKS5 proxy routes data packets from a specifically configured source through a remote server, and offers authentication methods to ensure that only authorized users can access this server. Whereas other types of proxies are limited to re-routing web-browser traffic, SOCKS5 proxies are more flexible.
Hey mason do you have a s5 proxy?
s5 by rip911proxies January 13, 2023
It means "back" in slovak language. Its original spelling in slovak language is "spat".
O chvilu som spat. {O chvilu som s5} - "I`ll be right back".
s5 by masi&trupik May 21, 2008
“I need some S5.”
“Yooo you tryna give up the S5?”
“S5”
S5 by mrphillis June 16, 2025