This word is a portmanteau combining the wordsEnemy and Mistress. A failed attempt with a girl you are trying to date and must avoid at all cost due to awkwardness and humiliation.
A lady, who you sharing memes with, particularly ones that you can't share with your wife. Not to be confused with memestress, although it's usually overlaps.
- Bro, you have convo with that girl for hours, are you having an affair?
- Nah, man, she just have really dark sense of humor. She is just my memistress.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.