To unknowingly slip Molly into a beverage just to watch what happens
Joey’s been real down lately. I’m going to mugsy him and see if it cheers him up.
by Steelone44 August 04, 2018
Get a Mugsy mug for your bunkmate José.
An person above god himself. Someone people pray to.
Eg. Nikola Tesla will follow mugsy
by Leonteje May 14, 2018
Get a Mugsy mug for your buddy Nathalie.
An annoying ass mother fucking dog that shits the entire house. This mother fucking bitch needs to burn in hell. It is extremely fucking obese. this is an abomination of nature that needs to be put out of its pointless fucking life.
by Renscada May 21, 2013
Get a Mugsy mug for your daughter-in-law Larisa.
An Acronym for McMaster University's gateway system in which causes physical and mental stress on its' students.

Most Useless Gateway System Invented.
Sarah had to use MUGSI yesterday, which caused her to smash her laptop.
by sweetmama. June 12, 2011
Get a Mugsi mug for your brother Manafort.
A picture taken of your favourite mug that is planned to be uploaded to Facebook, Myspace or any other sort of social networking website. You can usually see the person's favourite mug sitting where they like it most. When posted it is usually tagged with #mugsie. It is optional for the mug to be full or empty.
Bill: What was you doing Tom?

Tom: I was taking a Mugsie Bill, Wonna see?

Bill: My Gosh Tom! That is the best Mugsie I've ever seen!
by KangerooJ52 February 20, 2014
Get a Mugsie mug for your barber Nathalie.