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An officially recognized nickname for Missouri's flagship state university, the University of Missouri (MU), located in Columbia, Missouri. The University of Missouri was formerly designated as the University of Missouri-Columbia, under the University of Missouri System,which includes UMSL and UMKC, but "Columbia" was dropped after a decision made in late 2007.

"Mizzou" is ubiquitously used to refer to the university's athletic teams and the name can also be used to refer generally to the entire city of Columbia.

The origin of the nickname is unknown, but the first recorded usage of the word occurred in an alumni publication in 1906. As the university was formerly known as Missouri State University, it is possible that "Mizzou" came from a pronunciation of "MSU."
"I am really glad that I decided to go to Mizzou for my undergrad."

"Mizzou obviously pours a lot of their budget into athletics."

"The parties I've been to at Mizzou have all been really crazy."
by 2NIC October 17, 2009
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Oh youโ€™re just being alive? Iโ€™m horny too
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A.I heard the Mizzou tigers won yesterday 17 to 12

by unominus September 18, 2004
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slang for Missouri University. Often associated with the athetic program or the school.
"Pepole from Mizzou are pretty smart."
"Hey, did you see that Mizzou football game against Iowa State on Saturday? Mizzou won 17-14."
by AJ November 28, 2004
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1. The university of Missouri

2. The state of Missouri
I see Mizzou pulled a surprise victory over Duke in the 2009 Sweet Sixteen.

Let's go to Kansas City on the mizzou side for a few days.
by Mr. Terrence L. Trezvant March 26, 2009
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1. I couldn't get into DeVry so I went to Mizzou
2. Mizzou didn't even make the NIT
3. I can't spell Missouri so I'll just write Mizzou
4. I go to Mizzou, I am impotent.
5. My mom is my sister, I must go to Mizzou
by RainmanKC August 26, 2006
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