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A wonderful city in Western Montana where you can get high as a kite for $5, bike like a fucking maniac and go to a killer house party all in one day. Lots of hobos that are very fun to have casual conversations with, and a pretty decent football team. By far the most liberal town in montana with the most hot people.
Person 1: You look terrible! What'd you do this weekend?
Person 2: Missoula, man.
by grapesandcheeseparty October 01, 2011
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Nov 27 Word of the Day
A stupid person; it refers to the lack of surface area on an individual's brain. The general thought is that the more surface area (wrinkles, creases, etc.) a brain has, the smarter the person is. Conversely, a person with a smooth brain (no wrinkles) has less surface area and would therefore be stupid.
That fucking smooth brain put his shirt on backwards again...

That smooth brain is dumber than a pile of shit.
by Tip Tank May 14, 2011
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2
A pleasantly boring town in western Montana. It is probably the most culturally diverse town in Montana. The University of Montana is located here, and the general population is obsessed with going to Griz (mascot) football games. Also it is famous for it’s hippies. It has 2 Walmarts. Oh and, a river runs through it.
We're going to a Griz game in Missoula, and we're going to get totally wasted.
by Justtoast January 03, 2006
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3
The second largest and Most important city in the state of Montana and home of the University of Montana Grizzly football team 2010 population 68,000. Nicknames include the garden city and zoo town due to it sounding like Mi-zoo-la.
Missoula has doubled in size from the 1970s to today.
by grizmaster March 26, 2011
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4
Located in western Montana, a town where dogs outnumber people and are allowed to roam freely and defecate freely throughout the city. More Birkenstocks per capita than any other part of the world.
Tom: "Why are you wearing birkenstocks?"
Sue: "I'm headed for Missoula this weekend."
Tom: "Don't bother shaving."
by mlamson January 07, 2011
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5
The most liberal POS town in America. Where the hippies, mad jay walkers, and crazy bicyclists roam the streets. DO NOT ENTER! However there is an excellent Grizzly football team located in the town.
Q: Have you ever visited Missoula?

A:Unfortunately.
by Cucaracha255 July 06, 2009
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6
to take an extremely large and painful shit, usually filling the toilet, and any other containers near it (trash, sink, and possibly bathtub, depending on the intensity of the missoula.)

Home of the Griz.
Sorry guys. I gotta go destroy the toilet. I think I've got a Missoula coming
by Dvorak Shfilkins May 02, 2011
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