To instantly stop weeping over your huge vagina, grow a pair of hairy ones and get the fuck on with your day.

A casual invitation / threat used by an individual that is not afraid of fucking someone up.

be a man not a bitch; see training day where he tells him to hit that mexican garbage

When somebody is such a woman that they need to not just man up, but Man The Fuck Up. Can be shortened to MTFU. Usable on both genders and all species. Also, note that someone who gets some supresses the need to have this for a few days as they have already Manned Up enough.