(n.) A condition in which an individual is nagged and/or afflicted by a raving cow. Also known as marriage.
Poor Jim has a bad case of Mad Cow Disease.
by ChriSe7en July 13, 2009
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A legitimate medical term for the symptoms of P.M.S.

A woman with Mad Cow Disease is referred to as a mad cow.
Matt, "Thanks for taking me to the indian casino to play poker tonight. I had to get the fuck away from my wife before she drove me nuts."

Jeff, "You're welcome. I knew you needed it. According to my calender she's got mad cow disease this week."
by dooshkanew August 23, 2009
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Why is PMS called PMS? Because mad cow disease was already taken
by Blair* December 20, 2005
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Also known as Bovine Spongiform Encephalitis (BSE). It affects the brains of cows, and somtimes sheep too.
I wish curry would get mauled by a cow with mad cow disease
by Evil Tim September 21, 2003
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a fatal disease that affects both humans and cows. very talked about.
one damn cow was found with mad-cow in canada and everyone banned meat.
by megan March 4, 2004
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