Joe Mama Share definition Flag A clever name used to insult another individual's mother. It is a play on words that refers to the saying, "Yo mama!" Person 1: "Where's Joe?" Victim 1: "Joe? ... Joe who?" Person 1: "JOE MAMA!" Victim 1: *Proceeds to feel insulted* Joe Mama by B-Man February 2, 2004 Get the Joe Mama mug.