To isolate means to contain or withhold within a certain boundary. Nothing goes in, nothing goes out. Whatever is being isolated is protected from most means of harm - Yes, I said "most", because isolation doesn't always have its benefits. Believe me, I know.
We'll isolate this hot liquid in the thermos, it won't spill and it won't lose heat!
by TheSpectacularOne December 1, 2009
When a form of media makes you feel some sort of autophobia, triggered by an extreme fear of loneliness possibly due to the presence of a very few characters in that movie or show and also the type of world it was set in.

This term can also be used to describe the genre of that media.
Raja - Hey, did you watch that movie "Cast Away" by Tom Hanks?

Alex - Yes I did and it made me feel so isolic.

That game Ecco the Dolphin is so isolic, I felt really lonely while playing it.
by Pb32 July 6, 2018
Isolation is possibly the most boring thing in existence. It is the act of staying inside your house because you don’t want to catch a global pandemic of sort, most commonly COVID-19. It is recommended that you do isolate, even though while doing so you will probably be making TikToks or FaceTiming your toxic friends.
Have you been making TikToks and eating too much in isolation?
by it'smeyourcousin April 20, 2020
A condition of detachment or separation caused by using an iPod with headphones; being cut off or separated from others, despite their immediate presence, because the volume on iPod headphones is too loud.
My friend was trying to talk to me at the gym but I did not know because I was in iSolation.
by Ja$on June 16, 2007
Physical isolation=being away from any human beings to a point of madness

Mental isolation=being in a place full of the oppisote IQ
physical isolation=being put in a psyco hospital and then hanging yourself

mental isolation=being in a room full of dumb asses
by Nick D. Wolf October 25, 2008
Isolic is the feeling you get that a game can create tons of atmosphere* by making you feel lonely, isolated,


Silent hill games, Not scary but it does give a sense of isolation and a depressing atmosphere, mostly to do with running through dark hospitals, sewers and you just kind of go deeper and it feels like it gets more isolated rather than seeing the light at the end of the tunnel.
This game has a such a strong sense of isolation that i feel isolic just playing it!
by Jason Jehova July 10, 2018
In poker, a technique in which a player reraises a weaker player's bet, trying to play him heads-up (one on one) by making it expensive for any other players to call.
Bruce Lee: LaVar Arrington used isolation on Warren Sapp and forced Urlacher, Shaq and Busta Rhymes to fold.
Jose Contreras: LaVar is a fucking monster at poker, I'd never sit down with him.
by benny b from the bronx February 22, 2005