The Independent School League, also known as the ISL is a league of 16 relatively small New England Prep schools. The ISL has some of the best schools in the United States, most notably The Groton School, Middlesex School, and Roxbury Latin School, among others. The ISL is also well know for its strong athletics, especially in Football, Hockey, and Basketball.
Just because the ISL schools are smaller, doesn't mean they cant hold their own with the larger schools like Pillips Andover, and Chotae.
by F.I.S.T.14 October 4, 2009
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ISL: An abbreviation to "I Silently Laugh " this is used because 99.99% of the time one will send "LOL" they are not actually, laughing out loud.
*text msg*

Brandon: OMG did you see that video with the dogs leg stuck in the toilet
Jack: ISL YES!!!
by MGnT1999 November 20, 2013
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The Independant School League

A league of prep schools in N.E. that basically live to make fun of everyone else...ie, all hate public schools in unity, and then each school hates every other school too...a sad circle of false unity spread by lies and false faces, actuality, a group of individuals with temporary allies and enemies...
Milton Academy, of the ISL, played and smoked Nobles in football again...
by Mustang April 24, 2005
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Ugh.... a group of prep-schools in New England, surrounding Boston. Thayer Academy is the only one that remotely resembles an actual highscool.
"ISL football is a joke. Nobles sucks. Milton needs to get that giraffe out of their ass."
by Arrbear December 31, 2004
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Belle Island in Detroit, MI
A local hang out and driving strip.
"I'm bout to ride the isle and holla at some hoes"
by The Ski Mask July 8, 2006
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A small town in central Minnesota a really cool place

The opposite of Onamia
Braden: Isle is so much better then Onamia
Tate: True that!
by ISLEBALLER69 March 14, 2016
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