A hand grenade is a melon flavored alcoholic beverage sold at Tropical Isles on Bourbon Street in New Orleans. Marketed as the strongest drink on Bourbon Street, it is the equivalent of about 4 1/2 standard drinks
Paul drank three hand grenades and woke up the next morning in the gutter in New Orleans East with a sore anus.
by Playa N March 18, 2006
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When a session of fingering your girl starts to get a little dull, let it all end with a bang. Slip your fist inside of her vag, and without warning, extend all of your fingers as far as they can reach. The expression on her face should resemble some sort of surprise.
It was a rather uneventful night until I busted out my ammunition and let that bitch have a hand grenade.

When I saw the slightest hint of boredom in her eyes, I busted out a hand grenade that would have had the vietcong shaking in their boots.
by bdams August 17, 2003
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Mickey's Malt Liquor, sold in bottles which resemble a hand grenade.
"I'm in New York at the Puerto Rican day parade,
then at night I'm in New Orleans drinkin hand grenades." - Ludacris: Pimpin' All Over the World
by Kyle H September 22, 2005
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when you're about to rip a nasty fart and you put your hand right over your ass, capturing the smell, and then smelling it.
did you see dennis pull a hand grenade in class?
aw, man, that was naaasty!
by capndick August 9, 2010
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A gesture thrown by hand thumbs up or thumb up if only using one hand, ie the Fonz. A final affirmation for when everything is spot on. (Friendship goes with a bang!)
When you look at your hand in the thumbs up gesture side on, if you look closely at the four curled fingers that go into the palm and notice the edge of the knuckles it looks very much like the classic early Hand Grenade known as the pineapple hand grenade. Now looking back at your hand in the thumbs up gesture if you curl over your thumb and imagine its inside the ring that’s joined onto the pin, then move your thumb up as if to remove the pin thumbs up BOOM. A hand gesture thrown by the hand grenade Friendship goes with a bang!

by ThumbPin June 4, 2007
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Hand Grenade is the awesome Hedley song from the CD Famous Last Words
Megan- omg did you hear the new song Hand Grenade off of Hedleys new CD Famous Last Words?

Sally- nope

Megan- what a fucking fag you never heard Hand Grenade? pshh, i am dissapointed in you Sally

Sally- *goes home crying*
by sink_0r_swim October 31, 2007
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