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Hot Beef Injection: Judd Nelson from the John Hughes movie, Breakfast Club.
BENDER
               So...so!
                    (to Andrew and Claire)
               Are you guys like boyfriend/girl-
               friend?
                    (a beat)
               Steady dates?
                    (another beat)
               Lo--vers?
                    (another beat)
               Come on Sporto, level with me.  Do
               you slip her the hot...beef...
               injection?
H.B.I. by John March 6, 2003
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Man i want to give her the H.B.I. so bad tonight.
H.B.I. by hot carl December 12, 2003
Head Bitch In Charge... The female counterpart to the H.N.I.C or the H.M.F.I.C. The "Alpha female"... A lady boss...
I'm the H.B.I.C. of this patch of blue...
H.B.I.C by Shedevil925 January 14, 2006
Head Bitch In Charge
"I'm the H.B.I.C. around here!"
H.B.I.C by xXMehhh13Xx April 1, 2007
Head Bitch In Charge
Madonna is the H.B.I.C in her household.
H.B.I.C by repothegeneticopera March 22, 2009

H.B.I.C. 

An acronym for "head bitch in charge". Or if you wanna play nice it's "head beauty in charge".
I'm the H.B.I.C. in this area muthafucka!! You best do what I say *snapsnap* >:O
H.B.I.C. by head bitch in chaaarge October 19, 2008
It means "Head Bitch in charge" H.B.I.C
"hey joe.." , "yeah billy?" .."here comes the H.B.I.C" "shiiittee get back to work"

or

"heLL YeAAH BITcheS , BoWW DOwN tO dAh h.B.I.c " drunk emily said
H.B.I.C by BRUH2 October 11, 2017